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Pakistan EC disqualifies former PM Imran Khan in Toshakhana Case_我的网站

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A | Islamabad, Oct 21 (UNI) In a major legal victory for the ruling coalition on Friday, the Election Commission of Pakistan (ECP), in a consensus verdict in Toshakana reference, disqualified former prime minister Imran Khan and ruled that the PTI chairman is no more a member of National Assembly.
Criminal proceedings will be initiated against the PTI chairman for misdeclaration, the verdict said.
The ECP stated that Imran Khan submitted a false affidavit and was found involved in corrupt practices under Article 63(1)(p).
Under the said article, a lawmaker is disqualified for the time being from being elected or chosen as a member of the Majlis-e-Shoora (parliament) or of a provincial assembly.
The decision was taken unanimously by the ECP’s five-member bench but the Punjab member Babar Hassan Bharwana was not present today as he was unwell.
"As sequel to our abovementioned findings, facts available on record and keeping in view the argument of learned counsel for parties herein, we are of the considered opinion that the Respondent has become disqualified under Article 63(1)(p) of the Constitution read with Section 137,167 and 173 of the Elections Act,2017, consequently he ceases to be a member of the National Assembly of Pakistan and his seat has become vacant accordingly," the ECP order stated.
"As the respondent has made false statements and incorrect declarations, therefore he has also committed the offence of corrupt practices defined under Section 167 and 173 of the Elections Act,2017, punishable under Section 174 of the Elections Act, 2017. Office is directed to initiate legal proceedings and to take follow-up action under Section 190(2) of the Elections Act, 2017."
The verdict was announced amid tight security in the Red Zone where at least 1,100 police officials were deployed under the command of a senior superintendent of police to control the law and order situation in the area. The officer was assisted by five superintendents and six deputy superintendents of police.
The ECP had reserved its verdict in the Toshakhana case on September 19 after arguments were completed from both sides. A five-member bench of the ECP, headed by Chief Election Commissioner Sikandar Sultan Raja, heard the case.
Fawad Chaudry said the Election Commission’s attitude had been the worst. “We never pinned any hopes on it.”
“This is a shameful decision. They have disgraced the 220-million-strong-nation.”
Meanwhile, PPP Chairman Bilawal Bhutto said that the Election Commission of Pakistan has found Imran Khan guilty of corrupt practices and now stands disqualified.
“He who would spread lies about the alleged corruption of his political opponents has been caught red-handed," Bilawal said.
Moreover, PML-N Vice President Maryam Nawaz demanded Imran Khan be arrested after he was found guilty of corrupt practices.
“Pakistan's first certified liar and certified thief disqualified with irrefutable evidence of theft,” the PML-N leader said.
She alleged that the husband and wife together looted the national kitty.
In August 2022, National Assembly Speaker Raja Pervaiz Ashraf sent a reference to the ECP under Articles 62A, 63A, and 223, seeking former prime minister Imran Khan’s disqualification in the light of the Toshakhana scam, according to Geo news reports.
The disqualification reference was filed by Ali Gohar Khan, PML-N’s Mohsin Nawaz Ranjha, and five others.
The assessed value of the gifts has been put at Rs 142,042,100. The gifts were received between August 2018 and December 2021.
According to PML-N MNA Ranjha, Khan concealed information about the gift of watches by Saudi Arabia’s Crown Prince Mohammad bin Salman in his statement of assets submitted in 2018-2019.
This withholding of information is tantamount to lying which, according to Ranjha, is a crime under Section 137.
UNI GNK。这种蛋白质被称为SHMOOSE，是一种微小的"微蛋白"，由细胞内产生能量的线粒体中一个新发现的基因编码。

B | 该基因的突变使SHMOOSE微蛋白部分失活，并与四个不同队列中的阿尔茨海默病风险增加30%有关。据研究人员称，几乎25%的欧洲血统的人有这种蛋白质的突变版本。阿尔茨海默病是最普遍的痴呆症类型。

C | 这是一种渐进式的疾病，从轻微的记忆丧失开始，可能会导致丧失进行对话和对环境做出反应的能力。根据美国疾病控制与预防中心（CDC）的数据，在2020年，多达580万美国人患有阿尔茨海默病。这项研究于9月21日发表在《分子精神病学》杂志上。研究人员表示，这种以前未被发现的突变的巨大风险和高流行率都使它与其他涉及阿尔茨海默病的蛋白质有所区别。除了APOE4--这种疾病最有力的已知遗传风险因素--只有数量有限的其他基因突变被发现，而且这些突变只轻微地增加了不到10%的风险。此外，由于微蛋白的大小与胰岛素肽差不多，它可以很容易地被施用。这大大增加了它的治疗潜力。

D | Pinchas Cohen说：“这一发现为开发基于精准医疗的阿尔茨海默病疗法开辟了令人兴奋的新方向，重点是将SHMOOSE作为一个目标领域。

E | ”他是这项研究的资深作者，也是老年学、医学和生物科学的教授。

F | “对携带突变和产生突变蛋白的个体施用SHMOOSE类似物，可能证明对神经退行性疾病和其他衰老疾病有好处。”南加州大学神经科学博士毕业生Brendan Miller是该研究的第一作者。他利用大数据技术确定线粒体DNA中与疾病风险相关的基因变异。在分析发现一个基因突变增加了阿尔茨海默病风险、大脑萎缩和能量代谢后，Miller和他的同事发现突变的基因编码为SHMOOSE微蛋白，并开始研究其突变和默认形式。研究人员说，SHMOOSE是第一个用抗体和质谱法检测的线粒体DNA编码的微蛋白。看起来这种微蛋白修改了中枢神经系统的能量信号和新陈代谢。它在神经元的线粒体中被发现，其在脑脊液中的水平与阿尔茨海默病的生物标志物相关。各种细胞培养和动物实验表明，SHMOOSE部分通过栖息在线粒体的一个关键部分，即线粒体内膜，改变了大脑的能量代谢。

G | 阿尔茨海默病目前在美国被列为第六大死因。

H | 然而，CDC最近的估计表明，这种疾病可能排在第三位，仅次于心脏病和癌症，是老年人死亡的原因之一。尽管目前还没有治愈阿尔茨海默氏病的方法，但近年来在开发和测试新的治疗方法方面取得了重大进展。一个新兴的研究领域据Miller说，这些发现突出了微蛋白这一相对较新的领域的重要性。几十年来，科学家们主要通过考虑一组2万个大型蛋白质编码基因来研究生物学。然而，还有数十万个可能的编码微小微蛋白的基因已经被现代技术所揭示。Miller表示：“微蛋白领域仍然是如此的新。我们还不知道有多少微蛋白基因甚至是有功能的，而且从成千上万的名单中逐一研究潜在的微蛋白的成本实在是太昂贵和低效。我和我的同事用来检测SHMOOSE的方法显示了将大的遗传学数据与分子和生物化学技术相结合以发现功能性微蛋白的力量。